Summary. Macroglossia is a multifactorial condition that is almost always associated with a space-occupying mass of the tongue. The usual treatment is surgical resection. The typical medical conditions that lead to macroglossia have been described. The orofacial myologist should be alert to the presence of possible pathology of the tongue during orofacial examination, and refer suspected instances of macroglossia to an appropriate medical resource for definitive diagnosis and treatment.
Dolan, E. A., et al. (1989). Macroglossia: Clinical considerations, International Journal of Orofacial Myology, 15 (2), 4-7.